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What is the effect of amlodipine?
Amlodipine is the antagonist, a blood pressure-lowering drug from the class of Calcium. High blood pressure arises due to various mechanisms, one of these mechanisms, the Calcium is involved:
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The wall of our blood vessels is composed of different cells. The muscle cells of the vessel wall need for a contraction, among other things, a high concentration of intracellular Calcium. A contraction causes the blood vessels to constrict. As a result, the diameter of the vessel small, and the resistance that one must overcome by the blood flowing is greater. This increasing resistance is measurable, it is represented by the blood pressure values. Calcium is so crucial to the adjustment of the Vessel diameter is involved and therefore in the Regulation of blood pressure.
Amlodipine as a representative of the so-called calcium antagonists interfere with this mechanism by binding to the calcium channel of the blood vessel cells. Due to the antagonistic effect of amlodipine, the calcium channel is the openness probability of the channel decreases. Less Calcium enters from extracellular fluid into the muscle cells. The blood vessels are not narrowed by the blocking and the blood can flow without increased resistance. Amlodipine can be taken for the treatment of arterial hypertension, but also in the case of a white finger tables Angina pectoris. This Form of chest pain caused by spasms, so contractions of the heart supplying blood vessels. Due to this temporary lack of blood flow to the heart can lead to chest pain, amlodipine is also a positive influence.
What is a reduction in blood pressure with amlodipine?
A reduction in blood pressure with amlodipine improved the symptoms that can be caused by high blood pressure. Bleeding these include headaches, insomnia, and frequent nose. In addition, amlodipine reduced the risk of sequelae of elevated blood pressure. Especially dangerous is high blood pressure and atherosclerosis resulting in heart attacks or stroke. The underlying mechanism is the same for both incidents is the same: Due to the increased blood pressure, atherosclerotic Plaques form on the vessel walls. These Plaques can burst or parts \”blow off\”. This triggers a blood-clotting, and the blood closes the vessel either locally or blasted parts of the plug receptacle, a smaller blood. This is in the coronary arteries of the case, it comes to a heart attack. At the stroke of a Thrombus in a blood vessel of the head and causes a lack of oxygen, later for the treatment of life-threatening.
Less acutely dangerous, but also damaging life consequences of high blood pressure are kidney problems and therefore a lack of detoxification of the body as well as chronic fatigue due to the reduced quality of sleep. The blood pressure is lowered, for example with amlodipine permanently and optimally set, so the risk of complications can be greatly reduced.
Can I buy amlodipine without a prescription?
Tablets with the active ingredient amlodipine prescription are always subject to. Because the calcium antagonists must be taken in the case of some pre-existing conditions in any case, they must always be prescribed by a doctor. Even if you have taken amlodipine already, it must be in the Following are not freely sold. For example, after a heart attack or worsening heart failure amlodipine is contraindicated. The doctor can check for this prior to the re-Issue of the recipe, in order not to endanger you by taking.
What is the special feature of amlodipine to other high blood pressure?
Amlodipine has been compared to that of other calcium antagonists have the advantage that it needs to be taken due to its high half-time only once a day. In addition, the bioavailability of amlodipine is high, it is the entire substance passes so nearly in the bloodstream and is excreted directly without the Occurrence of the desired effect.
Furthermore, amlodipine has due to its high selectivity for the vascular cells, a low degree of side effects. It is therefore to be only minimal in unwanted Places of the organism, but specifically to the cells where it will block the calcium receptor.
In contrast to most of the other calcium it is not antagonists in heart failure is contraindicated. This is due to the fact that it lowers the force of contraction of the heart and, therefore, an existing heart failure not deteriorating. Amlodipine can be taken with beta or some other blood-pressure-nuclear-prescribed-blockers, in order to optimize their impact and on a further level of regulation of the blood pressure.