Paroxetine is an oral selective serotonin reuptake inhibitor that works similarly to sertraline, fluoxetine and citalopram. The effects of this drug are based on correcting the imbalance of neurotransmitters in the brain, which is thought to be responsible for the symptoms of depression. It’s been used for the symptoms of panic disorders, depression, post traumatic stress disorder, obsessive-compulsive disorders, social anxiety disorder and premenstrual dysphoric disorder.
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Dosage and administration
Paroxetine is available as tablets containing 10, 20, 30, and 40 mg of the active ingredient. There are also contained-release tablets available at 12.5, 25, and 37.5 mg, as well as 10 mg/5 ml suspension. The usual dosage is 20-60 mg (regular tablets) taken once a day, usually in the morning. It may take the drug up to 4 weeks to improve the symptoms, during which time it must be used regularly at the right dose.
Stopping Paroxetine treatment suddenly may cause symptoms like nausea, insomnia, nervousness and anxiety. You should stop taking this drug gradually, taking less and less as discussed with your health care provider.
As most other drugs, Paroxetine can cause side effects. In most cases, only mild side effects may be experienced, and only by a few percent of people being treated. The most commonly reported mild side effects include constipation, drowsiness, sweating, dry mouth, diarrhea, anxiety, insomnia, headaches, nausea, weakness and loss of appetite. Less common and more serious side effects include seizures, sexual dysfunction and increased blood pressure.
You should report any serious or bothersome side effects to your doctor to see if anything needs to be changed about your treatment. Paroxetine may cause suicidal thoughts in the short term. Regular visits to your doctor for the first several weeks of the treatment are required to make sure any dangerous symptoms are timely managed.