The active ingredient in clonidine is used in the treatment of hypertension. In addition, the drug is symptoms substance but also to the attenuation of withdrawal symptoms when alcohol or drug addiction. By taking it can lead to numerous side effects – including fatigue, dry mouth and headache. We will inform you in detail about effect, side effects and dosage of clonidine.
Effect of clonidine
Clonidine is primarily used for the treatment of high blood pressure (hypertension). The active ingredients in your body that less adrenaline and noradrenaline are released. Both of these messengers to ensure that the blood is propelled, pressure in the amount. Drops your concentration, relax and expand the blood vessels and the heart has to work less. All of this leads to the fact that the blood pressure drops.
In addition to high blood pressure, clonidine can also be supportive during a anesthesia, as well as to combat withdrawal symptoms. The active ingredient, for example, helps to dampen the withdrawal symptoms after a alcohol -, drug -, or Opioid dependence.
Side effect of clonidine
While you are taking clonidine, a number of side effects can occur. Among the most common side effects are fatigue, drowsiness, and dry mouth. Also can make headache, constipation, Nausea and vomiting, erectile dysfunction and a slowing of the heart beat is noticeable. Occasionally it can also cause skin reactions and itching.
Rarely, side effects such as dizziness, sleep disturbances, depression, mood changes, sensory disturbances, confusion and hallucinations. Also rarely it comes to weight gain due to water retention.
In order to avoid further side effects, should clonidine never abruptly, but slowly, step by step be discontinued. Otherwise, the so-called Rebound can occur phenomenon. This can lead to an excessive response by clonidine, resulting in a very fast and strong increase in blood pressure may occur.
Dosage of clonidine
Clonidine can be injected taken orally as a capsule or tablet as well as intravenously, intramuscularly or subcutaneously. In addition, the active substance in different doses. In General, should always be started with a low dose and be increased if necessary, then slowly.
If the doctor is not otherwise recommended, is started the treatment with a dose of 0.075 milligrams. If necessary, the dose can be increased then more. However, a dose adjustment should be done only after about two to four weeks.
Under certain circumstances, you should not take clonidine. This is especially the case if you are allergic to the active ingredient. Furthermore, clonidine is also the case of the following diseases is contraindicated and the Patient needs careful medical Monitoring:
- Low Blood Pressure
- Renal function disorders
- Heart rhythm disorders (AV-Block)
- Fresh Heart Attack
- Bradycardia less than 50 beats per Minute
- Severe Disorders Of Blood Circulation
- Severe disease of the coronary vessels
During pregnancy and lactation the drug should not be used. Also children may not be with the clonidine treated.
Clonidine is taken simultaneously with other drugs, can occur under certain circumstances, interactions. Tell your doctor therefore always be aware of what medications you regularly take. Among other things, interactions with the following drugs are known:
- Tricyclic Antidepressants
In addition, the intake of medications such as beta-blockers, which also influence the blood pressure should be avoided. Otherwise, it can lead to heart rhythm disorders, as well as a slowing of the heartbeat. Also, make sure to take at the same time with the active ingredient alcohol, since otherwise the effect of clonidine may be enhanced.