Loratadine Relieves Hay Fever
- 1 Effect of the Antihistamine
- 2 Loratadine for hay fever and eczema
- 3 Side effects of loratadine
- 4 Dosage of loratadine
- 5 Interactions and contraindications
- 6 More on the subject of hay fever
- 7 Pregnancy and lactation
Loratadine is an antihistamine used to treat hay fever as well as skin diseases such as eczema and hives. By taking symptoms such as Sneezing, eye burning, or itching can be alleviated. In comparison to the older antihistamines, loratadine is not significantly less side effects, as it acts as sedating. In this regard, it is with the active ingredient cetirizine which is also used for the treatment of hay fever.
Effect of the Antihistamine
Loratadine is just as cetirizine is a H1-antihistamine second Generation. In contrast to the first-Generation antihistamines loratadine and cetirizine have no influence on the Central nervous system and thus have no sedative properties. Thus, they cause fewer side effects than antihistamines, which belong to the first Generation.
Loratadine blocks the body’s histamine H1-receptors and ensures that the messenger substance histamine is not the more bind to these. Thus, histamine is not, or at least not to its full effect, and unpleasant symptoms such as redness of the skin, eyes burning or itching.
Loratadine for hay fever and eczema
In the case of allergic rhinitis (hay fever) and relieves loratadine burn the typical symptoms such as Sneezing, nasal flow, itching Eyes, and eyes. It also has decongestant action on the nasal mucosa and is used, therefore, in the case of sinusitis.
Also in atopic dermatitis, the active ingredient is used more and more frequently. It reduces itching and makes the redness of the skin. Similarly, the drug addiction can also in other skin diseases such as urticaria, which is characterized by a strong wheal formation on the skin, alleviate the discomfort.
Side effects of loratadine
When taking loratadine relatively few side effects compared to other antihistamines. Because, unlike first-Generation antihistamines, which acted through its CNS binding often sedating is loratadine exactly as cetirizine CNS-accessible. Nevertheless, can occur due to the administration of the two active ingredients to side effects.
Among the side effects that can make it through the ingestion of loratadine more noticeable, headache, fatigue, nervousness and increase in Appetite. Very rarely allergic reactions were, dry mouth, dizziness, Nausea, stomach mucosa inflammation, insomnia, hair loss, liver dysfunction, and heart rhythm disorders were observed.
Dosage of loratadine
Medications with loratadine over the counter available in pharmacies. It is available in various dosage forms, including tablets and effervescent tablets. The exact dosage of the drug you should discuss with a doctor or pharmacist.
In General, the recommended adult dose of ten milligrams is given once daily. Children can also get ten milligrams, if you weigh more than 30 kilograms. For lower weight children five milligrams are recommended grams. Patients with liver damage should only take all of two days each dose.
If you forget to take a dose, you can do this in a timely manner. You take the active ingredient, for example, usually in the morning, is also a dose in the afternoon or evening. The next intake date is imminent, however, immediately, you should not make up the missed dose. In any case, you should take two tablets at once.
Interactions and contraindications
Loratadine is broken down in the body by the enzyme CYP3A4. Be taken at the same time substances that inhibit the activity of the enzyme, may enhance effects and side effects of the Antihistamine. Can interactions occur with the following resources:
- Ketoconazole (Antifungals)
- Erythromycin (Macrolide Antibiotic)
- Cimetidine (H2-Antihistamine)
- HIV-protease inhibitors
- Grapefruit juice
Loratadine should not be used if Hypersensitivity to the active substance. In the case of Liver dysfunction, the active ingredient should be used, if at all, only under strict medical supervision.
If you are planning to do a skin test, should not be taken the drug at least two days prior to testing. Otherwise, the results of the Tests can be distorted.
More on the subject of hay fever
Cetirizine is used to treat hay fever Antihistamines Hay fever – Pollen fly again!
Pregnancy and lactation
During pregnancy loratadine should not be taken. So far, there is no secure knowledge about whether the substance may cause damage to the unborn child.
It is certain, however, that it is excreted during the lactation period in the mother’s milk. The active ingredient should be taken Advantage of therefore, during this time, only after a careful cost-benefit analysis by the treating physician. The decisive factor is that the Benefit to the mother outweighs the potential harm to the child.