Pills for enuresis – a list of drugs for the treatment of urinary incontinence in adults and children
- 1 Rules of drug therapy
- 2 Desmopressin
- 3 Oxybutynin
- 4 Tricyclic antidepressants
- 5 Other groups of drugs
Rules of drug therapy
Medicines for enuresis should be prescribed exclusively by a doctor. It is impossible to independently cancel the medication, change the dosage recommended by a specialist, adjust or change the course of therapy.
If a patient has become intolerant of the prescribed medication, side effects have appeared, you should contact a specialist: he will replace the remedy and select the other, the most suitable one. Any prescription should be under the supervision of a physician.
Read also … Enuresis – what it is and how to get rid of bed-wetting
To date, the following incontinence tablets are actively used in adults and children:
- Aimed at reducing urine formation (Desmopressin).
- Having anticholinergic action (oxybutynin).
- Tricyclic antidepressants (imipramine).
- Preparations of other groups (Canephron, antibacterial agents, nootropics).
The drug is a synthetic analogue of the antidiuretic hormone – vasopressin. Available in pill form called Minirin. The drug Adiuretin contains the same active ingredient, but is produced in the form of a solution for injection and nasal drops.
Desmopressin is safe in the treatment of enuresis in children, and it is used to eliminate urinary incontinence in adults. Selectively acting on certain receptors of the kidneys, the drug reduces the intensity of urine formation at night.
Minirin is available in dosages of 0.1 and 0.2 mg by the Swedish company Ferring Pharmaceuticals. The initial dose for children older than five years and adults – 0.1-0.2 mg 3 times a day. Then, depending on the individual response of the body, the doctor adjusts the daily dosage.
The course of therapy is an average of 3 months, during treatment it is necessary to limit fluid intake, especially in the evening. The question of the need for a subsequent course of therapy is decided by the doctor after a week break in taking the pills.
A side effect of Minirin can be hyponatremia. Clinical symptoms of this electrolytic imbalance are headache, dyspepsia, nausea, and vomiting. The occurrence of side effects, as well as individual intolerance are grounds for the doctor to cancel the pills.
The tool refers to the antagonists of M-cholinergic receptors and has a spasmolytic effect on the smooth muscles of the bladder. Oxybutyrin (Driptan) increases the capacity of the urine-retaining organ, reduces the detrusor’s spasm, restrains urination and reduces their number.
The release form of the drug – tablets in a dosage of 5 mg. The therapeutic dose is 0.3-0.4 mg / kg of body weight per day and is divided into 2-3 doses.
Tablets can be administered to children after 5 years and adults. Side effects of treatment with Driptan can be: dry mouth, a feeling of heat in the whole body, constipation, general weakness, abdominal pain.
The drug is contraindicated in case of individual intolerance, intestinal atony, glaucoma, severe colitis, obstructive uropathy, pregnancy and breastfeeding.
This group of drugs include Imipramine, Melipramine. The mechanism of action of tricyclic antidepressants is still under study. It is proved that they improve the night’s sleep of children with enuresis, increase the capacity of the bladder and reduce its contractility, because of which the episodes of involuntary urination are reduced.
The dosage of tablets is selected by the doctor individually for each age group. In some cases, the prescription of Imipramine may be limited due to serious side effects: psychomotor and mental disorders, marked cardiotoxic effects, and development of gastrointestinal diseases are possible. Tricyclic antidepressants are currently being used much less frequently in the treatment of enuresis than a few decades ago.
Other groups of drugs
In case of secondary incontinence, other pills may be recommended, which are prescribed by specialists depending on the cause of the enuresis.
If involuntary urination is caused by an infection of the genitourinary system, the doctor recommends a course of antibiotic therapy to the patient. For chronic cystitis, pyelonephritis, a course prophylactic treatment with herbal pills is recommended 2 times a year. Canephron has a positive effect in preventing relapse.
In case of neurosis-like conditions provoking enuresis, nootropics have a good effect in therapy: Pantogam, Piracetam, Encephabol. Picurilon with enuresis is prescribed in age dosages and, like all drugs that improve metabolic processes in nerve cells, is recommended for course therapy for a period of 2-3 months, followed by a repetition if necessary.
Treatment of enuresis in adults and children includes an important component: drug therapy. In the pharmaceutical market there are tablets that can increase the capacity of the bladder, reduce or completely eliminate the episodes of uncontrolled urination. It is important to remember that pharmacotherapy and the selection of necessary drugs should be carried out by the attending physician.