The principle of action of drugs for the cleansing of blood vessels: effective prevention of vascular pathologies
- 1 When and why to clean the vessels?
- 2 Effective drugs
- 3 Additional recommendations
All this leads to a deterioration in the blood supply to the brain tissue, neurological disorders, increased pressure. The latter factor is often the cause of hemorrhagic strokes, fraught with persistent disability or death. Modern medicine offers several groups of drugs that cleanse the blood vessels and restore cerebral circulation.
When and why to clean the vessels?
The presence of chronic diseases of the cardiovascular, endocrine systems is the basis for the diagnosis and purification of cerebral vessels. For example, in diabetes mellitus, a violation of carbohydrate metabolism in most cases causes an imbalance of lipids. At the same time, the blood thickens, in erythrocytes with platelets, the tendency to adhesion and gluing increases. Blood clots and atherosclerotic plaques constrict the vessel lumen, preventing normal cerebral circulation:
- weakness, shortness of breath appear;
- disturbed with constant headaches with darkening of the eyes, dizziness;
- deterioration of concentration, memory, general performance.
If you leave these signs without attention, the pathological condition will progress. Over time, the deposits on the walls of the artery completely overlap its lumen, the blood stops flowing to a certain part of the brain, and it dies.
A plaque rupture or a clot rupture cause hemorrhagic strokes, thromboembolism, which in most cases is fraught with death. Therefore, it is necessary to clean the vessels.
If a clinical examination revealed the need to clean up arteries from cholesterol and blood clots, the doctor selects an individual treatment regimen. The choice of drugs depends on the diagnosis, as well as the patient’s condition, the presence of concomitant pathologies.
Medicines can be administered in the form of oral medication, droppers or injections for cleaning vessels. You can take pills on an outpatient basis, at home, and intravenous medication requires placement in a hospital. What groups of drugs are usually used?
This group of drugs is used for the prevention and treatment of thrombosis. Platelet aggregation, along with their adhesion (attachment to the walls of the arteries) leads to blockage of the bloodstream. Small blood clots constrict the lumen of the vessel, increasing blood pressure in it, and large closes completely, which leads to ischemia of the brain area. In addition, a loose clot can cause thromboembolism. Antiplatelet agents prevent adhesion of shaped elements, as well as disaggregate already formed blood clots.
The most effective of them is Xanthinol nicotinate. In addition to antiplatelet properties, this drug also exhibits vasodilators and blocks slow calcium channels. The combined effect provides a high efficacy of the drug, which is available in the form of a solution and tablets.
The tablet form contains the active substance in an amount of 150 mg, which is a single dose. Take daily need 3 tablets. With a solution of 15%, intramuscular or intravenous injections are performed. Xanthineol nicotinate can not be administered in the first trimester of pregnancy, with heart failure, bleeding, stomach ulcer.
The most effective group of lipid-lowering drugs prescribed for atherosclerosis. These drugs for cleaning vessels block the synthesis of endogenous cholesterol in the human body by inhibiting the enzyme HMG-CoA reductase. Accordingly, the total concentration of low-density lipoproteins decreases, the formation and growth of cholesterol plaques stops. The most effective drugs of the category are Atorvastatin, Simvastatin of domestic and foreign production.
Available in tablets with a minimum dosage of 10 mg. They need to take only 1 time per day, and the effectiveness of the active substance does not depend on the meal. The initial single dose is usually 10 mg, the maximum does not exceed 80 mg. Medications rarely cause unwanted adverse reactions in the form of digestive disorders.
Contraindications are individual intolerance, severe liver and kidney failure. Statins are not recommended for pregnant and lactating women, since their effects on the fetus and young children are not well understood.
Another class of effective lipid-lowering drugs. Unlike statins, their main target is not cholesterol, but very low density lipoproteins – triglycerides of fatty acids. Due to the activation of a special enzyme, these compounds are destroyed, and at the same time the production of beneficial HDL is stimulated. The preparations of the group also possess fibrinolytic and antiaggregant activity, which additionally accelerates the cleansing of blood vessels.
Fibrates are available in the form of capsules or tablets under various trade names: Fenofibrate, Lipantil, Exlip, Traykor, Grofibrate. There is a fairly extensive list of contraindications, which include pregnancy, lactation, age under 18, liver and kidney failure, hypersensitivity, gallbladder pathology, hypothyroidism, alcoholism.
Sometimes there can be negative reactions from different organs and their systems. Per day is taken 1 tablet or capsule, the digestibility of which does not depend on the presence in the gastrointestinal tract of food.
Calcium ions, penetrating through special channels in the membranes inside the muscle cells, increase the excitability of myocytes. Blocker drugs have the ability to inhibit the flow of ions, thus lowering the tone of smooth muscle. As a result, the vessels expand, the microcirculation is activated, and the pressure in the cerebral arteries decreases. Verapamil became the first in the group of calcium antagonists; later Diltiazem, Cinnarizine, Amlodipine, Nifedipine and others were synthesized.
Cinnarizine – the most commonly prescribed vascular cleaning tablets, effective and inexpensive. Appointed with cerebral atherosclerosis in the initial stage, has a minimum number of contraindications, which include periods of pregnancy and breastfeeding, younger children, as well as individual intolerance to the active substance. Side effects are rare, even with prolonged use. Dosage tablets – 25 mg, you need to take one every 8 hours after meals.
Vessels can also be cleaned with drugs that reduce blood viscosity. Anticoagulants reduce its clotting by acting directly or indirectly on different parts of the coagulation process. In the first case, the active substances reduce the activity of coagulation factors directly in the blood, and the anticoagulants of indirect action violate their synthesis in the liver cells. The latter include drugs such as Warfarin, Dicoumarin, Antitrombin and others.
The use of anticoagulants has many limitations and contraindications. For example, warfarin should not be taken in the first three and last months of pregnancy, with liver pathologies, stomach ulcers, the risk of bleeding, endocarditis, aneurysm. Of great importance is drug compatibility, because in combination with some drugs, the effectiveness of warfarin decreases, with others it increases, which can lead to complications. A single dose is usually 5 mg (2 tablets of 2.5 mg), taken strictly 1 time in 24 hours.
Correctors of cerebral circulation
The group includes various drugs that activate blood flow through multi-vector exposure. Cleansing the arteries of cholesterol and blood clots contribute to:
- decrease in the muscle tone of the cerebral vessels, their expansion;
- activation of metabolism in brain tissue;
- prevention of platelet aggregation;
- slowing down the flow of calcium ions.
For example, an inexpensive, but effective drug Vinpocetine positively affects the cerebral circulation with virtually no side effects. There are also few contraindications to its use: lactation, pregnancy, ischemic heart disease, arrhythmia, hypersensitivity. Available in dosage forms of injection solution and tablets of 5 mg. Inside the medicine is taken every 12 hours, 5 or 10 mg. The recommended duration of treatment is 2 months.
In case of any diseases, taking multivitamin complexes always complements the main purposes, because without these compounds the body cannot function normally. For vascular health, several types of vitamins are of particular importance.
This is primarily niacin or nicotinic acid. He takes part in the metabolism of fats, so it is mandatory to be appointed for atherosclerosis. In addition, B-group vitamins, tocopherol antioxidants and ascorbic acid, which strengthen the vascular wall, are helpful.
You can take medicine only after examination and medical appointment. Many drugs pose a threat to health and life when used uncontrolledly, and the effectiveness of therapy depends on the individual characteristics of the patient. It is important to strictly observe the dosage, the timing of treatment, and the compatibility of medications with food. If necessary, intravenous drug administration is recommended to visit the day hospital.
Cleaning vessels with medical methods must necessarily be combined with a special diet. All foods high in saturated fat, sugar, fried, spicy, pickled foods are excluded from the menu. It is allowed to steam, boil or bake. Tonic drinks, alcohol is also prohibited (as well as smoking). In the diet should prevail vegetables, cereals, meat or fish, low-fat varieties, dairy products with a low mass fraction of fat. Strengthen the effectiveness of drug treatment is also moderate exercise: gymnastics, walking on the street, swimming.